👉 ACBDI, or Acetyl-CoA Dehydrogenase Complex, is a crucial enzyme complex in cellular metabolism that plays a central role in energy production. It catalyzes the oxidative decarboxylation of acetyl-CoA to form acetyl-CoA carboxylate and NADH, linking glycolysis and fatty acid synthesis. This complex consists of multiple subunits, including three core enzymes (HMG-CoA synthase, HMG-CoA lyase, and acyl-CoA synthetase) and several regulatory factors. The Acetyl-CoA Dehydrogenase Complex is pivotal in regulating the flow of carbon from carbohydrates to fatty acids, making it essential for both energy generation and lipid biosynthesis. Dysregulation of ACBDI activity can lead to metabolic disorders, highlighting its importance in maintaining cellular homeostasis.
